Mailing address
Department of Otorhinolaryngology and Head and Neck Surgery
1st Faculty of Medicine, Charles University, Univeristy Hospital Motol and Homolka
V Uvalu 84, 150 06 Prague 5
CZECH REPUBLIC
Education and Qualification
2011 – 2017 First Faculty of Medicine, Charles University, Prague
09/2015 – 01/2016 Universität Rostock, Universitätsmedizin Rostock
2017 - 2022 residency in Otorinolaryngology
2017 - 2026 Doctoral studies – Experimental surgery, Charles University
Topic: Targeted polymer macromolecules in experimental chemotherapy
treatment of head and neck squmous cell carcinoma
Supervisor: doc. MUDr. Jan Bouček, PhD
Employment history
2017 - 2022 Department of Otorinolaryngology and Head and Neck Surgery of 1st Faculty of
Medicine and Motol University Hospital, Resident
2017 - 2022 Laboratory of Tumor immunology, Institute of Microbiology of the Czech
Academy of Sciences, doctoral student
2022 – present Department of Otorinolaryngology and Head and Neck Surgery of 1st Faculty of
Medicine and Motol University Hospital, Senior Physician
2022 – present Department of Otorinolaryngology and Head and Neck Surgery of 1st Faculty of
Medicine and Motol University Hospital, Assistant Professor
Selected
Fellowships and Conference Participation
04/2025 33rd Stuttgart Advanced Course for Rhinoplasty, Stuttgart, Germany
11/2024 Department of Otorhinology, Erlangen, Germany (prof. Koch), observership, 2W
10/2023 Department of Otorhinology, Varese, Italy (prof. Castelnuovo), observership, 2W
06/2023 The 7th World Congress of the International Federation of Head and Neck, speaker
Oncologic Societies, Rome, Italy, invited speaker
03/2023 Prague Meeting on Tumor Therapy and Imaging, CZ, invited speaker
11/2021 Institute for Advanced Biosciences, Grenoble, Dr. JL Coll, research stay, 2W
04/2025 33rd Stuttgart Advanced Course for Rhinoplasty, Stuttgart, Germany
11/2019 Institute for Advanced Biosciences, Grenoble, Dr. JL Coll, internship, 2W
Prague, 1.11.2025
Selected publications
- Kaňa M, Braunová A, Starenko D, et al. Overcoming P-glycoprotein-mediated multidrug resistance in cancer cells through micelle-forming PHPMA-b-PPO diblock copolymers for doxorubicin delivery. J Control Release. 2025;381:113645. doi:10.1016/j.jconrel.2025.113645. IF = 11,5; Q1
- Ebrahimi, E., Sangphukieo, A., Park, H.A. et al. Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites. Nat Commun 16, 8787 (2025). IF = 15,7; Q1
- Pola R, Grosmanová E, Pechar M, Horák D, Krunclová T, Pankrác J, Henry M, Kaňa M, Bouček J, Šefc L, Coll JL, Etrych T. Stimuli-Responsive Polymer Nanoprobes Intended for Fluorescence-Guided Surgery of Malignant Head-and-Neck Tumors and Metastases. Adv Healthc Mater. 2023 Jun 8:e2301183.
- Kana M, Kalfert D, Lukes P, Zabrodsky M, Plzak J. C-reactive protein as an early marker of postoperative leakage in patients after endoscopic laser assisted Zenker's diverticulotomy. Eur Arch Otorhinolaryngol. 2023 Apr;280(4):2007-2016.
- Tavares MR, Hrabankova K, Konefał R, Kana M, Rihova B, Etrych T, Sirova M, Chytil P. HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicinesfor Oncotherapy. Pharmaceutics. 2021; 13, 179.
- Braunova A, Kana M, Kudlacova J, Kostka L, Boucek J, Betka J, Sirova M, Etrych T. Micelle-forming block copolymers tailored for inhibition of P-gp-mediated multidrug resistance: structure to activity relationship. Pharmaceutics. 2019; 11, 579. IF = 4,213
- Kana M, Kana R, Povysil C. New developments in understanding of histological structure of human ear cartilage. Folia Biol (Praha). 2019;65(5-6):256-64.
- Povýšil C, Kaňa M, Zámečník L, Vaľová Z, Hanuš T. Podoplanin (D2-40) is a reliable marker of urinary bladder myofibroblasts (telocytes). Folia Biol (Praha). 2014;60(6):286-9.
Professional membership
Czech Society of Otorhinolaryngology and Head and Neck Surgery; Czech Society of Immunology; European Rhinologic Society – Junior member